Lawton is the county seat of Comanche County, which was created in 1901 from the Comanche, Kiowa and Caddo lands of Indian Territory. Comanche County was open for settlement on August 16, 1901 by lottery.
Comanche County's economy is primarily centered on government, manufacturing and retail trade industries. The Lawton MSA had a Gross Domestic Product of $4.89 billion in 2010 with half ($2.66 billion) in the government sector. Private industries accounted for $2.23 billion in GDP in which manufacturing ($451 million), real estate and rental and leasing ($305 million), and retail trade ($255 million) were the largest fields.
The largest occupation fields includes the office and administrative support occupations field which has 6,760 employed, the food preparation and serving related occupations, which employs 4,630, and the sales and related occupations, which has 4,150 employed.
The region has three cities and seven towns as well as the Fort Sill military instillation and Wichita Mountains Wildlife Refuge. The landscape of the county is typical of the Great Plains with flat topography and gently rolling hills, while the areas in the north are marked by the Wichita Mountains. Interstate 44 and three major US Highways serve the county by ground, while the Lawton-Fort Sill Regional Airport serves the county by air.